2-Chloro-4,6-dimethoxy-1,3,5-triazine → 8-Cyclodecyl-3-(4,6-dimethoxy-[1,3,5]triazin-2-yl)-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one hydrochloride
반응식
Cl.[CH:2]1([N:12]2[CH2:28][CH2:27][C:15]3([N:19]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[CH2:18][NH:17][C:16]3=[O:26])[CH2:14][CH2:13]2)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[Cl:29][C:30]1[N:35]=[C:34]([O:36][CH3:37])[N:33]=[C:32]([O:38][CH3:39])[N:31]=1>>[ClH:29].[CH:2]1([N:12]2[CH2:28][CH2:27][C:15]3([N:19]([C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=4)[CH2:18][N:17]([C:30]4[N:35]=[C:34]([O:36][CH3:37])[N:33]=[C:32]([O:38][CH3:39])[N:31]=4)[C:16]3=[O:26])[CH2:14][CH2:13]2)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1참가 물질
3
실험 절차
The title compound, white solid, m. p. 216° C. and MS: m/e=509.5 (M+H+) was prepared in accordance with the general method of example 24 from 8-cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one hydrochloride and 2-chloro-4,6-dimethoxy-[1,3,5]triazine.
출처 및 근거
- ORD 기록
- ord-f0fd7f195ee04def83fa87d20edb147a
- 출처 데이터셋
- uspto-grants-2000_03