Hydrogen Peroxide → Dibenzothiophene sulfoxide

HRID 1639485

반응식

HRID 1639485 반응식
[CH:1]1[C:9]2[C:8]3[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=3[S:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[OH:14]O.O>FC(F)(F)C(O)=O>[CH:1]1[C:9]2[C:8]3[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=3[S:6](=[O:14])[C:5]=2[CH:4]=[CH:3][CH:2]=1

참가 물질

5

반응물 3

HCID 784Hydrogen PeroxideHCID 962WaterHCID 3023Dibenzothiophene

생성물 1

HCID 13898Dibenzothiophene sulfoxide

시약·촉매·용매 1

HCID 6422Trifluoroacetic acid용매

반응 조건

온도
60 °C

실험 절차

Dibenzothiophene (20.0 g) is suspended in 80.0 ml of trifluoroacetic acid at room temperature. Into the suspension is slowly dropped 12.4 ml of 30% aqueous hydrogen peroxide while cooling with ice so as to maintain the reaction temperature around 60° C. After completion of dropping, the reaction solution is stirred at room temperature for 30 minutes. After the reaction, the reaction solution is added to 1,000 ml of water to precipitate crystals. The crystals are recovered by filtration and washed with water. The obtained crystals are recrystallized with acetonitrile to obtain 19.2 g of dibenzothiophene-S-oxide.

후처리

  1. temperaturewhile cooling with ice so as
  2. customAfter the reaction
  3. customto precipitate crystals
  4. filtrationThe crystals are recovered by filtration
  5. washwashed with water
  6. customThe obtained crystals are recrystallized with acetonitrile

출처 및 근거

ORD 기록
ord-f1f36577d45342e3902ca24789186a6f
출처 데이터셋
uspto-grants-2012_02
특허 번호
US08110333B2

연결된 노트

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