참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Methylindanone | HCID 249262 | — |
| 반응물 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Methylindan-1-one oxime | HCID 73454082 | 89.8% |
반응 단계
A mixture of 2-methyl-1-indanone (10 g, 0.0684 mol) and hydroxylamine hydrochloride (9.5 g, 0.1368 mol) in ethanol was stirred at 60° C., and a solution of sodium acetate (16.8 g, 0.2052 mol) in water added. The resulting mixture was then heated at reflux for 90 minutes, then cooled and the solid filtered. The crude product was washed with water and filtered to give 2-methyl-indan-1-one oxime (9.9 g, yield 81%), mp. 82-91° C., in 90% purity.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08114991B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_02 |
|---|
| ORD ID | ord-bc3dafd1fd074be09964f9c4bf057cae |
|---|
| 출처 메모 | uspto-grants-2012_02 |
|---|
