Toluene → 1-{4-[9-[(1R,2S,3R,4S)-2,3-Dihydroxy-4-(4-methyl-pyrazol-1-yl)-cyclopentyl]-6-(2,2-diphenyl-ethylamino)-9H-purin-2-ylamino]-cyclohexyl}-3-(3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-urea Trifluoroacetate

반응식

[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[NH2:8][CH:9]1[CH2:14][CH2:13][CH:12]([NH:15][C:16]2[N:24]=[C:23]3[C:19]([N:20]=[CH:21][N:22]3[C@@H:25]3[CH2:29][C@H:28]([N:30]4[CH:34]=[C:33]([CH3:35])[CH:32]=[N:31]4)[C@@H:27]([OH:36])[C@H:26]3[OH:37])=[C:18]([NH:38][CH2:39][CH:40]([C:47]3[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=3)[C:41]3[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=3)[N:17]=2)[CH2:11][CH2:10]1.C1(C)C=CC=CC=1.CC(O)C.[N:64]1[CH:69]=[CH:68][CH:67]=[CH:66][C:65]=1[N:70]1[CH2:75][CH2:74][CH:73]([NH:76][C:77](N2C=CN=C2)=[O:78])[CH2:72][CH2:71]1>C(Cl)Cl>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[OH:37][C@@H:26]1[C@H:27]([OH:36])[C@@H:28]([N:30]2[CH:34]=[C:33]([CH3:35])[CH:32]=[N:31]2)[CH2:29][C@H:25]1[N:22]1[CH:21]=[N:20][C:19]2[C:23]1=[N:24][C:16]([NH:15][CH:12]1[CH2:11][CH2:10][CH:9]([NH:8][C:77]([NH:76][CH:73]3[CH2:72][CH2:71][N:70]([C:65]4[CH:66]=[CH:67][CH:68]=[CH:69][N:64]=4)[CH2:75][CH2:74]3)=[O:78])[CH2:14][CH2:13]1)=[N:17][C:18]=2[NH:38][CH2:39][CH:40]([C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1)[C:47]1[CH:48]=[CH:49][CH:50]=[CH:51][CH:52]=1