Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Bromo-2-chloro-3-methylpyridine → tert-butyl (3aS,6aS)-5-(6-chloro-5-methyl-3-pyridinyl)hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Bromo-2-chloro-3-methylpyridine | HCID 285434 | — |
| 반응물 | 1,1-Dimethylethyl (3aS,6aS)-hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate | HCID 29949089 | — |
| 생성물 | tert-butyl (3aS,6aS)-5-(6-chloro-5-methyl-3-pyridinyl)hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate | HCID 86584376 | 41% |
반응 단계
The product from Example 15E and 5-bromo-2-chloro-3-methylpyridine were processed as described in Example 1E to provide the title compound (41% yield). MS (DCI/NH3) m/z 338/340 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08119635B2 |
| 출처 데이터셋 | uspto-grants-2012_02 |
| ORD ID | ord-0c65e10edfbf4183897f6d67b569c9a4 |
| 출처 메모 | uspto-grants-2012_02 |