Benzoylhydrazine → 1-(Morpholin-4-ylcarbonyl)-N'-(phenylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carbohydrazide
반응식
[N:1]1([C:7]([N:9]2[CH2:14][CH:13]([C:15]3[CH:20]=[CH:19][C:18]([O:21][C:22]([F:25])([F:24])[F:23])=[CH:17][CH:16]=3)[CH2:12][CH:11]([C:26]([OH:28])=O)[CH2:10]2)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[C:29]1([C:35]([NH:37][NH2:38])=[O:36])[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[N:1]1([C:7]([N:9]2[CH2:14][CH:13]([C:15]3[CH:20]=[CH:19][C:18]([O:21][C:22]([F:25])([F:23])[F:24])=[CH:17][CH:16]=3)[CH2:12][CH:11]([C:26]([NH:38][NH:37][C:35]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)=[O:36])=[O:28])[CH2:10]2)=[O:8])[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1참가 물질
3
실험 절차
100 mg (0.25 mmol) of the compound from Example 44A and 65 mg (0.50 mmol) of benzenecarbohydrazide were reacted according to the General Method 11A.
출처 및 근거
- ORD 기록
- ord-48d8effcf93b4be8929b087b4a9a11d4
- 출처 데이터셋
- uspto-grants-2012_02
- 특허 번호
- US08119663B2
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