N'-Hydroxy-2-methylpropanimidamide → HCID 58002215, 화합물

반응식

[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:14][N:13]([C:15]([N:17]3[CH2:20][CH:19]([OH:21])[CH2:18]3)=[O:16])[CH2:12][CH:11]([C:22](O)=[O:23])[CH2:10]2)[CH:5]=[CH:6][C:7]=1[CH3:8].O[N:26]=[C:27]([NH2:31])[CH:28]([CH3:30])[CH3:29]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:10][CH:11]([C:22]3[O:23][N:31]=[C:27]([CH:28]([CH3:30])[CH3:29])[N:26]=3)[CH2:12][N:13]([C:15]([N:17]3[CH2:20][CH:19]([OH:21])[CH2:18]3)=[O:16])[CH2:14]2)[CH:5]=[CH:6][C:7]=1[CH3:8]

참가 물질

반응물 2

HCID 2794833N'-Hydroxy-2-methylpropanimidamide

HCID 58002370HCID 58002370, 화합물

생성물 1

HCID 58002215HCID 58002215, 화합물

실험 절차

72 mg (0.22 mmol) of the compound from Example 134A and 43 mg (0.33 mmol) of N′-hydroxy-2-methylpropanimidamide were reacted according to the General Method 2. Yield: 17 mg (19% of theory)

출처 및 근거

ORD 기록: ord-e5cb0a1b89ad4ccd8df2847e76c52749
출처 데이터셋: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08119663B2

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