N-(tert-butoxycarbonyl)-L-aspartic acid → N,N'-[[(S)-(1-t-butoxyformamido)ethylene]dicarbonyl]di-beta-alanine dibenzyl ester
반응식
[C:1]([O:5][C:6]([NH:8][C@H:9]([C:14]([OH:16])=O)[CH2:10][C:11]([OH:13])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:17]([O:24][C:25](=[O:29])[CH2:26][CH2:27][NH2:28])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([O:24][C:25](=[O:29])[CH2:26][CH2:27][NH:28][C:11]([CH2:10][C@H:9]([NH:8][C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:7])[C:14]([NH:28][CH2:27][CH2:26][C:25]([O:24][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:29])=[O:16])=[O:13])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1참가 물질
3
실험 절차
N-(t-butoxycarbonyl)-L-aspartic acid is coupled with two equivalents of β-alanine benzyl ester to give N,N'-[[(S)-(1-t-butoxyformamido)ethylene]dicarbonyl]di-β-alanine dibenzyl ester, m.p. 109°-110° C.
출처 및 근거
- ORD 기록
- ord-fddf1ab4d3d94aef8575dc50d7ecedcd
- 출처 데이터셋
- uspto-grants-1995_07
- 특허 번호
- US05430024