Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → Dimethylaminopropyl thiohydantoin valine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | l-Valine, ethyl ester | HCID 87182 | — |
| 반응물 | 3-((Dimethylamino)phenyl isothiocyanate | HCID 141351 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Dimethylaminopropyl thiohydantoin valine | HCID 86748773 | — |
반응 단계
Valine ethyl ester (0.01 mol) in 30 ml of anhydrous methanol was reacted with dimethylaminopropyl isothiocyanate (0.01 mol) for 3 hours at 50° C. The solution was made basic by the addition of two equivalents of triethylamine. Solvent was removed by rotary evaporation. Water was added to the solid residue and the residue was filtered and washed with water. The residue was dissolved in methanol and analyzed by FAB/MS. The expected product, dimethylaminopropyl thiohydantoin valine (MH+=244), was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05432093 |
| 출처 데이터셋 | uspto-grants-1995_07 |
| ORD ID | ord-433c315089c44813a8711837dd95fa0e |
| 출처 메모 | uspto-grants-1995_07 |