Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 4,6-Bis (1,1-dimethylethyl)-5-hydroxy-2-pyrimidine carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 4,6-Bis(1,1-dimethylethyl)-5-[(2-methoxyethoxy)-methoxy]-2-pyrimidinecarbonitrile | HCID 19922986 | — |
| 생성물 | 4,6-Bis (1,1-dimethylethyl)-5-hydroxy-2-pyrimidine carbonitrile | HCID 15294897 | 68.2% |
반응 단계
According to the procedure of Example 18, 4,6-bis(1,1-dimethylethyl) -5-[(2-methoxyethoxy)methoxy]-2-pyrimidine carbonitrile (9.1 g, 28.3 mmol) is treated with trifluoroacetic acid to give 4,6-bis(1,1-dimethylethyl)-5-hydroxy-2-pyrimidine carbonitrile (4.5 g, 68%); mp 203°-205° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05432181 |
| 출처 데이터셋 | uspto-grants-1995_07 |
| ORD ID | ord-c489861f71f146a69ac58151c26e9de4 |
| 출처 메모 | uspto-grants-1995_07 |