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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1647547생성일: 2026년 10월 26일

2-(2-Chlorophenyl)-4-(piperidin-1-yl)butanenitrile → alpha-(2-Chlorophenyl)-alpha-[2-[(1-methylethyl) (phenylmethyl)amino]ethyl]-1-piperidine butanenitrile

https://huagongshe.com/reaction/1647547

반응식

참여 물질

역할이름HCID투입량
반응물2-(2-Chlorophenyl)-4-(piperidin-1-yl)butanenitrileHCID 11043596—
반응물N-(2-chloroethyl)-N-(1-methylethyl)benzenemethanamine, monohydrochlorideHCID 24185321—
용매Dimethyl SulfoxideHCID 679—
생성물alpha-(2-Chlorophenyl)-alpha-[2-[(1-methylethyl) (phenylmethyl)amino]ethyl]-1-piperidine butanenitrileHCID 11112943—

반응 단계

alkylating α-(2-chlorophenyl)-1-piperidine butanenitrile with N-(2-chloroethyl)-N-(1-methylethyl)benzenemethanamine, monohydrochloride in the presence of base and dimethyl sulfoxide to give α-(2-chlorophenyl)-α-[2-[(1-methylethyl) (phenylmethyl)amino]ethyl]-1-piperidinebutane nitrile;

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05432284
출처 데이터셋uspto-grants-1995_07
ORD IDord-9dc16d8664ff409cbf686b37e19e6bc9
출처 메모uspto-grants-1995_07