4-(2-Chloroethyl)morpholine → HCID 10158541, 화합물

반응식

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:12]2[CH:17]([CH2:18][CH3:19])[S:16][C:15](=[O:20])[NH:14][N:13]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH2:10][F:11].Cl[CH2:22][CH2:23][N:24]1[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1>>[O:27]1[CH2:28][CH2:29][N:24]([CH2:23][CH2:22][N:14]2[N:13]=[C:12]([C:5]3[CH:6]=[CH:7][C:8]([O:9][CH2:10][F:11])=[C:3]([O:2][CH3:1])[CH:4]=3)[CH:17]([CH2:18][CH3:19])[S:16][C:15]2=[O:20])[CH2:25][CH2:26]1

참가 물질

반응물 2

HCID 767274-(2-Chloroethyl)morpholine

HCID 19358044HCID 19358044, 화합물

생성물 1

HCID 10158541HCID 10158541, 화합물

실험 절차

In analogy to Example 4, by reacting 5-(3-methoxy-4-fluoromethoxyphenyl)-6-ethyl-3,6-dihydro-1,3,4-thiadiazin-2-one with 1-chloro-2-morpholinoethane, 2-morpholinoethyl-5-(3-methoxy-4-fluoromethoxyphenyl)-6-ethyl-3,6-dihydro-1,3,4-thiadiazin-2-one is obtained.

출처 및 근거

ORD 기록: ord-1545f37bc28547588949eae0ea19c408
출처 데이터셋: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05434149

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