Quinoline, 3-bromo-4-nitro-, 1-oxide → HCID 10641049, 화합물

반응식

Br[C:2]1[CH:3]=[N+:4]([O-:15])[C:5]2[C:10]([C:11]=1[N+:12]([O-:14])=[O:13])=[CH:9][CH:8]=[CH:7][CH:6]=2.[N:16]12[CH2:23][CH2:22][CH2:21][C:20]1([CH2:24][CH2:25][NH2:26])[CH2:19][CH2:18][CH2:17]2>>[N:16]12[CH2:23][CH2:22][CH2:21][C:20]1([CH2:24][CH2:25][NH:26][C:2]1[CH:3]=[N+:4]([O-:15])[C:5]3[C:10]([C:11]=1[N+:12]([O-:14])=[O:13])=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH2:19][CH2:18][CH2:17]2

참가 물질

반응물 2

HCID 84235Quinoline, 3-bromo-4-nitro-, 1-oxide

HCID 107969772-(Hexahydro-1H-pyrrolizin-7a-yl)ethanamine

생성물 1

HCID 10641049HCID 10641049, 화합물수율 87.4%

실험 절차

3-Bromo-4-nitroquinoline 1-oxide and 2-(1-azabicyclo[3.3.0]octan-5-yl)ethylamine were reacted in the same manner as in Example 1 to obtain the titled compound in a yield of 87.4%.

출처 및 근거

ORD 기록: ord-4d8f6900ec2c44b2971414ff1a4e2823
출처 데이터셋: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05434165

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