(Hexahydro-1H-pyrrolizin-7A-YL)methanamine → HCID 10852527, 화합물

반응식

Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[N:15]12[CH2:22][CH2:21][CH2:20][C:19]1([CH2:23][NH2:24])[CH2:18][CH2:17][CH2:16]2>>[N:15]12[CH2:22][CH2:21][CH2:20][C:19]1([CH2:23][NH:24][C:2]1[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[CH:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13])[CH2:18][CH2:17][CH2:16]2

참가 물질

반응물 2

HCID 10654304(Hexahydro-1H-pyrrolizin-7A-YL)methanamine

HCID 122284651-Chloro-2-nitronaphthalene

생성물 1

HCID 10852527HCID 10852527, 화합물수율 84.1%

실험 절차

1-Chloro-2-nitronaphthalene and (1-azabicyclo[3.3.0]octan-5-yl)methylamine were reacted in the same manner as in Example 1 to obtain the titled compound in a yield of 84.1%.

출처 및 근거

ORD 기록: ord-8c924c06c56b4f8c8d7651c0f28c43ee
출처 데이터셋: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05434165

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