Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Carbonate → 2-(1-Amidino-4-piperidinyl)-5-[(2-methoxycarbonyl-ethyl)-aminocarbonyl]-1-methyl-benzimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Carbonate | HCID 10340 | — |
| 반응물 | S-Ethylisothiuronium bromide | HCID 200213 | — |
| 반응물 | 5-[(2-Methoxycarbonyl-ethyl)-aminocarbonyl]-1-methyl-2-(4-piperidinyl)-benzimidazole | HCID 19921265 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(1-Amidino-4-piperidinyl)-5-[(2-methoxycarbonyl-ethyl)-aminocarbonyl]-1-methyl-benzimidazole | HCID 19921162 | — |
반응 단계
Prepared from 5-[(2-methoxycarbonyl-ethyl)-aminocarbonyl]-1-methyl-2-(4-piperidinyl)-benzimidazole and S-ethylisothiourea-hydrobromide by heating to 100° C. for 4 hours in dimethylformamide in the presence of sodium carbonate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05434150 |
| 출처 데이터셋 | uspto-grants-1995_07 |
| ORD ID | ord-3203693e9a7b471988dc7a71f97095a1 |
| 출처 메모 | uspto-grants-1995_07 |