2,2,6-Trimethyl-5-phenyl-2H,4H-1,3-dioxin-4-one → 6-methyl-5-phenyl-3-(1,1,2,2-tetramethylpropyl)-2,3-dihydro-4H-1,3-oxazin-4-one

HRID 1648196노트

반응식

HRID 1648196 반응식
[C:1]1([C:7]2[C:8](=[O:16])O[C:10](C)(C)[O:11][C:12]=2[CH3:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C=[N:18][C:19]([CH3:25])([CH3:24])[C:20]([CH3:23])([CH3:22])[CH3:21]>C1(C)C(C)=CC=CC=1>[CH3:13][C:12]1[O:11][CH2:10][N:18]([C:19]([CH3:25])([CH3:24])[C:20]([CH3:23])([CH3:22])[CH3:21])[C:8](=[O:16])[C:7]=1[C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 2

HCID 131570242,2,6-Trimethyl-5-phenyl-2H,4H-1,3-dioxin-4-oneHCID 19918950N-methylene-1,1,2,2-tetramethylpropylamine

생성물 1

HCID 199189556-methyl-5-phenyl-3-(1,1,2,2-tetramethylpropyl)-2,3-dihydro-4H-1,3-oxazin-4-one수율 46.7%

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

A mixture of 5-phenyl-2,2,6-trimethyl-2h,4h-1,3-dioxin-4-one (0.65 g), N-methylene-1,1,2,2-tetramethylpropylamine (0.54 g) and xylene (2 ml) was heated at reflux for 30 minutes for reaction. The reaction mixture was purified by silica gel chromatography to obtain the captioned compound (0.40 g).

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 30 minutes for reaction
  3. customThe reaction mixture was purified by silica gel chromatography

출처 및 근거

ORD 기록
ord-138763b0d79946bead6d76574318ce58
출처 데이터셋
uspto-grants-1995_07
특허 번호
US05436224

반응 노트

불러오는 중…