반응식
CS(O[CH2:6][CH2:7][O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[O:15][CH:16]([CH3:18])[CH3:17])(=O)=O.[Cl:19][C:20]1[CH:21]=[C:22]2[C:26](=[CH:27][CH:28]=1)[NH:25][CH:24]=[C:23]2[CH2:29][C:30]([NH2:33])([CH3:32])[CH3:31].N1C2C(=CC=CC=2)C(CC(N)(C)C)=C1>>[ClH:19].[NH:25]1[C:26]2[C:22](=[CH:21][CH:20]=[CH:28][CH:27]=2)[C:23]([CH2:29][C:30]([NH:33][CH2:6][CH2:7][O:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[O:15][CH:16]([CH3:17])[CH3:18])([CH3:31])[CH3:32])=[CH:24]1참가 물질
4
실험 절차
Proceeding as in Example 3, but replacing 2-(cyclopropylmethyloxy)phenoxyethyl methanesulfonate with 2-[2-(prop-2-yloxy)phenoxy]ethyl methanesulfonate and [2- (5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine with [2-(1H-indol-3-yl)-1,1-dimethylethyl]amine, gave [2-(1H-indol-3-yl)-1,1-dimethylethyl]{2- [2-(prop-2-yloxy)phenoxy]ethyl}amine hydrochloride, m.p. 164°-166° C.
출처 및 근거
- ORD 기록
- ord-7f2a32e666614368bca28aab58404ddd
- 출처 데이터셋
- uspto-grants-1995_07
- 특허 번호
- US05436264
연결된 노트
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