Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(1H-indol-3-yl)-2-methylpropan-2-amine → [2-(1H-indol-3-yl)-1,1-dimethylethyl]{-[2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(1H-indol-3-yl)-2-methylpropan-2-amine | HCID 9353 | — |
| 반응물 | 5-Chloro-alpha,alpha-dimethyl-1H-indole-3-ethanamine | HCID 13260 | — |
| 반응물 | 2-[2-(2-Methylprop-1-yloxy)phenoxy]ethyl methanesulfonate | HCID 15289997 | — |
| 생성물 | [2-(1H-indol-3-yl)-1,1-dimethylethyl]{-[2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride | HCID 19919953 | — |
반응 단계
Proceeding as an Example 3, but replacing 2-[2-(cyclopropylmethyloxy)phenoxy]ethyl methanesulfonate with 2-[2-(2-methylprop-1-yloxy)phenoxy]ethyl methanesulfonate and [2-(5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine with [2- (1H-indol-3-yl)-1,1-dimethylethyl]amine, gave [2-(1H-indol-3-yl)-1,1-dimethylethyl]{-[2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride, m.p. 147°-148° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05436264 |
| 출처 데이터셋 | uspto-grants-1995_07 |
| ORD ID | ord-82c864aed14a4276955dd18dbaccb624 |
| 출처 메모 | uspto-grants-1995_07 |