Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Acetate → 1-(2-Aminothiazol-4-yl)-1-propencarboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | Thiourea | HCID 2723790 | — |
| 반응물 | Ethyl 2-ethylidene-4-chloro-3-oxobutyrate | HCID 54518096 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 1-(2-Aminothiazol-4-yl)-1-propencarboxylic acid ethyl ester | HCID 54404371 | — |
반응 단계
to a solution of 190 g of the product of example 81 in 400 ml tetrahydrofuran were added first a solution of 82 g sodium acetate in 150 ml of water and then 76 g thiourea. The solution was stirred at room temperature for 20 hours, then the THF was distilled off and acetic acid ethyl ester was added to the residue.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04416880 |
| 출처 데이터셋 | uspto-grants-1983_11 |
| ORD ID | ord-9b4705d37edf4c80b2ad9f87b172ad31 |
| 출처 메모 | uspto-grants-1983_11 |