Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfoxide → 7,7-Diphenylhept-6-enoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Benzophenone | HCID 3102 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | (5-Carboxypentyl)triphenylphosphanium bromide | HCID 2779280 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 7,7-Diphenylhept-6-enoic acid | HCID 336480 | 70.6% |
반응 단계
The reaction was carried out as in Example 87 using the following reagents: sodium hydride (56% dispersion in oil; 8.6 g); dimethylsulfoxide (100 mL), (5-carboxypentyl)triphenylphosphonium bromide (37.64 g); benzophenone (18 g) and tetrahydrofuran (100 mL). The acid, isolated in the normal manner, was crystallized from hexane to give 16.3 g of 7,7-diphenyl-6-heptenoic acid, mp 71.5°-72.5° C. A portion was recrystallized from hexane to give the analytical sample, mp 72.5°-73.5° C. Anal. Calculated for C19H20O2 : C, 81.40; H, 7.19. Found: C, 81.61; H, 7.40.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04927838 |
| 출처 데이터셋 | uspto-grants-1990_05 |
| ORD ID | ord-3fd35f1fca6a408a90b075a3dea125e5 |
| 출처 메모 | uspto-grants-1990_05 |