2-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethan-1-amine → 2-(Pyridin-4-yl)-4-(3,4-ethylenedioxyphenethylamino)-6-trifluoromethyl-thieno-[2,3-d]-pyrimidine

반응식

[CH2:1]1[O:2][c:3]2[cH:4][c:5]([CH2:6][CH2:7][NH2:8])[cH:9][cH:10][c:11]2[O:12][CH2:13]1.[Cl:14][c:15]1[c:16]2[c:17]([n:18][c:19](-[c:21]3[cH:22][cH:23][n:24][cH:25][cH:26]3)[n:20]1)[s:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]2>>[CH2:1]1[O:2][c:3]2[cH:4][c:5]([CH2:6][CH2:7][NH:8][c:15]3[c:16]4[c:17]([n:18][c:19](-[c:21]5[cH:22][cH:23][n:24][cH:25][cH:26]5)[n:20]3)[s:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]4)[cH:9][cH:10][c:11]2[O:12][CH2:13]1

참가 물질

반응물 2

HCID 37470272-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethan-1-amine

HCID 184600504-Chloro-2-(pyridin-4-yl)-6-trifluoromethyl-thieno-[2,3-d]-pyrimidine

생성물 1

HCID 184600382-(Pyridin-4-yl)-4-(3,4-ethylenedioxyphenethylamino)-6-trifluoromethyl-thieno-[2,3-d]-pyrimidine

출처 및 근거

ORD 기록: ord-d9b2654ecc92469d81a71af17486b95c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…