Dichloromethane → 1-amino-N-(5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl)cyclopropane-1-carboxamide

반응식

[Cl:36][CH2:37][Cl:38].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35].[cH:1]1[cH:2][n:3][c:4]2[n:5]1-[c:6]1[c:7]([cH:25][cH:26][cH:27][cH:28]1)[CH2:8][CH2:9][CH:10]2[NH:11][C:12](=[O:13])[C:14]1([NH:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:15][CH2:16]1>>[cH:1]1[cH:2][n:3][c:4]2[n:5]1-[c:6]1[c:7]([cH:25][cH:26][cH:27][cH:28]1)[CH2:8][CH2:9][CH:10]2[NH:11][C:12](=[O:13])[C:14]1([NH2:17])[CH2:15][CH2:16]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 67234386tert-butyl N-[1-(5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-ylcarbamoyl)cyclopropyl]carbamate

생성물 1

HCID 672342911-amino-N-(5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl)cyclopropane-1-carboxamide

출처 및 근거

ORD 기록: ord-aab14dda6b6d4389bb66e6bf50489c27
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

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