Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → 1-Phenyl-3-(2-furanyl)-2-propyne-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | Cornforth reagent | HCID 2724130 | — |
| 반응물 | alpha-[(2-Furanyl)ethynyl]-benzenemethanol | HCID 20076917 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 1-Phenyl-3-(2-furanyl)-2-propyne-1-one | HCID 14401734 | — |
반응 단계
Place pyridinium dichromate (0.75 g, 2 mmol) and methylene chloride (15 mL) under argon atmosphere and cool to 0° C. Add α-[(2-furanyl)ethynyl]-benzenemethanol (297 mg, 1.5 mmol). Stir overnight while slowly warming to room temperature. Dilute with ethyl ether and filter the chromium salts. Purify by silica gel chromatography to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05409942 |
| 출처 데이터셋 | uspto-grants-1995_04 |
| ORD ID | ord-a42f66b7f987487399e9614f7813cf37 |
| 출처 메모 | uspto-grants-1995_04 |