Ammonia → HCID 178511997, 화합물

HRID 1654886노트

반응식

HRID 1654886 반응식
[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][O:7][C:8]2[C:9]([NH:14][C:15]([NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=S)=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1.[NH3:26]>>[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][O:7][C:8]2[C:9]([NH:14][C:15]([NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[NH:26])=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 222AmmoniaHCID 20076930HCID 20076930, 화합물

생성물 1

HCID 178511997HCID 178511997, 화합물

실험 절차

A mixture of N-[3-(4-chlorobenzyloxy)pyrid-2-yl]-N'-phenylthiourea (3.00 g, 0.008 mol), yellow mercuric oxide (2.17g, 0.01 mol) and methanolic ammonia solution (40 ml) was stirred for 48 hours. The solvent was removed in vacuo and the black residue was boiled with chloroform and filtered hot. Evaporation of the solvent and recrystallisation from acetonitrile gave the desired product. Yield 1.8 g (63%), m.p. 173°-174 ° C.

후처리

  1. customThe solvent was removed in vacuo
  2. filtrationfiltered hot
  3. customEvaporation of the solvent and recrystallisation from acetonitrile

출처 및 근거

ORD 기록
ord-3845f06657174bff9a63e23c9e062f0e
출처 데이터셋
uspto-grants-1995_04
특허 번호
US05409943

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