Benzhydrylamine → N-(Benzimidazol-2-yl)benzhydrylamine

HRID 16551

반응식

HRID 16551 반응식
Cl[C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[CH:11]([NH2:24])([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[N:6]1[C:5]2[CH:7]=[CH:8][CH:9]=[CH:10][C:4]=2[NH:3][C:2]=1[NH:24][CH:11]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

참가 물질

3

반응물 2

HCID 7036BenzhydrylamineHCID 785722-Chlorobenzimidazole

생성물 1

HCID 11709202N-(Benzimidazol-2-yl)benzhydrylamine

실험 절차

The title compound was prepared from 2-chlorobenzimidazole and benzhydrylamine by Procedure A. The product was isolated by preparative LCMS to give the title compound as the free base (white solid, mp 255-258° C.). MS(ES+) m/z 300 ([M+1]+, 100). 1NMR (DMSO-d6) δ 6.20 (d, 1H), 6.75-7.65 (m, 15H), 10.5 (s, 1H).

후처리

  1. customThe product was isolated by preparative LCMS

출처 및 근거

ORD 기록
ord-9cf6243bc6fd45f0a01c176917e554cd
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07737167B2

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