Ethyl Acetate → HCID 178488162, 화합물

반응식

[CH3:1][N:2]([CH3:24])[C:3]1[C:8](C)=[CH:7][N:6]=[C:5]([CH2:10][S:11][C:12]2[NH:16][C:15]3[CH:17]=[CH:18][C:19]([O:21][CH3:22])=[CH:20][C:14]=3[N:13]=2)[C:4]=1[Cl:23].C(OCC)(=[O:27])C>>[CH3:1][N:2]([CH3:24])[C:3]1[CH:8]=[CH:7][N:6]=[C:5]([CH2:10][S:11]([C:12]2[NH:16][C:15]3[CH:17]=[CH:18][C:19]([O:21][CH3:22])=[CH:20][C:14]=3[N:13]=2)=[O:27])[C:4]=1[Cl:23]

참가 물질

반응물 2

HCID 8857Ethyl Acetate

HCID 178488123HCID 178488123, 화합물

생성물 1

HCID 178488162HCID 178488162, 화합물

실험 절차

Substituting 2-(4-dimethylamino-3-chloro-2-pyridylmethylthio)-5-methoxy-(1H)-benzimidazole (3.43 g) for 2-(4-dimethylamino-3-chloro-5-methyl-2-pyridylmethylthio)-5-methoxy-(1H)-benzimidazole and using corresponding molar proportions of the other reagents in the method of Example 16, gave 2-(4-dimethylamino-3-chloro-2-pyridylmethylsulphinyl)-5-methoxy-(1H)-benzimidazole, (0.83 g), m.p. 113°-114° from ethyl acetate.

출처 및 근거

ORD 기록: ord-6a02e3f507aa434bb0bc9a600b5ae158
출처 데이터셋: uspto-grants-1993_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05250527

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