2-Butanone, 3-bromo- → HCID 19787526, 화합물
반응식
[C:1]([NH:4][C:5]1[CH:6]=[C:7]([CH:9]=[C:10]([CH3:12])[CH:11]=1)[NH2:8])(=[O:3])[CH3:2].Br[CH:14]([CH3:18])[C:15](=O)[CH3:16]>CN(C)C=O>[C:1]([NH:4][C:5]1[CH:6]=[C:7]2[C:9]([C:14]([CH3:18])=[C:15]([CH3:16])[NH:8]2)=[C:10]([CH3:12])[CH:11]=1)(=[O:3])[CH3:2]참가 물질
4
실험 절차
9 g of 3-acetamido-5-methylaniline are dissolved in 20 ml of dimethylformamide and 3.2 ml of 3-bromobutan-2-one are then added. The mixture is left at ambient temperature for 1 hour and the temperature is then raised to 100°-110° C. for one hour. The mixture is cooled and poured into 100 ml of ice-water. The precipitate is drained and washed successively with 50 ml of distilled water, 20 ml of ethanol and 20 ml of isopropyl ether. 4.2 g of white precipitate are obtained.
후처리
- temperaturethe temperature is then raised to 100°-110° C. for one hour
- temperatureThe mixture is cooled
- washwashed successively with 50 ml of distilled water, 20 ml of ethanol and 20 ml of isopropyl ether
출처 및 근거
- ORD 기록
- ord-946d25eb59e14301b062b0240541b520
- 출처 데이터셋
- uspto-grants-1993_10
- 특허 번호
- US05254135
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