Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromobenzyl bromide → 1-Bromo-2-(methoxymethyl)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromobenzyl bromide | HCID 76965 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 1-Bromo-2-(methoxymethyl)benzene | HCID 12927162 | 87% |
반응 단계
685 g (2.74 mol) of o-bromobenzyl bromide are refluxed together with 2.74 mol of a 30% strength sodium methylate solution in methanol for 15 hours. The mixture is cooled and then concentrated, the residue is taken up in ethyl acetate, and the solution is washed with water. The organic phase is dried over sodium sulfate and then concentrated. 478.2 g (87%) of product are obtained as a colorless liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05254717 |
| 출처 데이터셋 | uspto-grants-1993_10 |
| ORD ID | ord-ac990156198e4b42a08f29931fbd0efa |
| 출처 메모 | uspto-grants-1993_10 |