돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1657415생성일: 2026년 10월 26일

5,6,7-Trimethoxy-1,2,3,4-tetrahydroisoquinoline → 4-Amino-6,7,8-trimethoxy-2-(5,6,7-trimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)quinazoline

https://huagongshe.com/reaction/1657415

반응식

참여 물질

역할이름HCID투입량
반응물5,6,7-Trimethoxy-1,2,3,4-tetrahydroisoquinolineHCID 270529—
반응물2-Chloro-6,7,8-trimethoxyquinazolin-4-amineHCID 3015804—
생성물4-Amino-6,7,8-trimethoxy-2-(5,6,7-trimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)quinazolineHCID 21416703—

반응 단계

The procedure described in Example 1 was followed to prepare the above compound, starting from 4-amino-2-chloro-6,7,8-trimethoxyquinazoline and using 5,6,7-trimethoxy-1,2,3,4-tetrahydroisoquinoline as the reagent of choice on the same molar basis as before. In this particular instance, the final product was obtained as the free base compound, m.p. 193°-195°C.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US03960861
출처 데이터셋uspto-grants-1976_06
ORD IDord-446d14531ab74d25b15b6976d781fe78
출처 메모uspto-grants-1976_06