Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphonic acid → N-methylpyrrolidone-5,5-diphosphonic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphonic acid | HCID 407 | — |
| 반응물 | Phosphorus trichloride | HCID 24387 | — |
| 반응물 | 3-(Methylcarbamoyl)propanoic acid | HCID 292050 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-methylpyrrolidone-5,5-diphosphonic acid | HCID 12886162 | — |
반응 단계
28.5 gm of succinic acid monomethylamide (0.216 mol) were melted with 35.4 gm of H3PO3 (0.432 mol) at 70°C and then slowly mixed with 37.8 ml of PCl3 (0.432 mol). After an additional 5 hours at 70°C, the product was hydrolyzed with 300 ml of H2O. Filtration with activated carbon at the boiling point yielded a clear solution from which the N-methylpyrrolidone-5,5-diphosphonic acid was precipitated with ethanol and acetone. Crude yield 4.2 gm (7% of the theory).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03960888 |
| 출처 데이터셋 | uspto-grants-1976_06 |
| ORD ID | ord-03c27f84e5744cf1996243df3e845b70 |
| 출처 메모 | uspto-grants-1976_06 |