Aniline → 2-Phenylamino-N-(2-methyl-4-sulphamoylphenyl)-acetamide

HRID 1658209노트

반응식

HRID 1658209 반응식
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([S:12](=[O:15])(=[O:14])[NH2:13])=[CH:8][C:7]=1[CH3:16])=[O:4].[NH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[C:18]1([NH:17][CH2:2][C:3]([NH:5][C:6]2[CH:11]=[CH:10][C:9]([S:12](=[O:15])(=[O:14])[NH2:13])=[CH:8][C:7]=2[CH3:16])=[O:4])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

참가 물질

3

반응물 2

HCID 6115AnilineHCID 215288492-Chloro-N-(2-methyl-4-sulphamoylphenyl)-acetamide

생성물 1

HCID 215288562-Phenylamino-N-(2-methyl-4-sulphamoylphenyl)-acetamide수율 44%

실험 절차

2-Chloro-N-(2-methyl-4-sulphamoylphenyl)-acetamide (13.1g) and aniline (9.5 g) were heated together 21/2 hr on a water bath at 90°. The mixture was worked up as in Example 1(b) to yield 7 g beige crystals, m.p. 195°-196°

출처 및 근거

ORD 기록
ord-a25644f5dae245b39611f5eb2fbb0219
출처 데이터셋
uspto-grants-1976_06
특허 번호
US03963706

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