Formaldehyde → Benzenesulfonamide, 3-chloro-4-(3-(4-methylphenyl)-5-oxo-1-imidazolidinyl)-

HRID 1658217노트

반응식

HRID 1658217 반응식
[CH3:1][C:2]1[CH:23]=[CH:22][C:5]([NH:6][CH2:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([S:17](=[O:20])(=[O:19])[NH2:18])=[CH:13][C:12]=2[Cl:21])=[O:9])=[CH:4][CH:3]=1.[CH2:24]=O>C(O)C.O>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:6]2[CH2:7][C:8](=[O:9])[N:10]([C:11]3[CH:16]=[CH:15][C:14]([S:17](=[O:19])(=[O:20])[NH2:18])=[CH:13][C:12]=3[Cl:21])[CH2:24]2)=[CH:22][CH:23]=1

참가 물질

5

반응물 2

HCID 712FormaldehydeHCID 21528835HCID 21528835, 화합물

생성물 1

HCID 3041010Benzenesulfonamide, 3-chloro-4-(3-(4-methylphenyl)-5-oxo-1-imidazolidinyl)-

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

2-(p-Methylanilino)-N-(2-chloro-4-sulphamoylphenyl)-acetamide (15g) was dissolved in ethanol (200 ml) and paraformaldehyde (2.5 g) in water (400ml) added thereto. The mixture was refluxed for 3 hours, cooled in ice/water and filtered to yield the title compound (6.45g), m.p. 223°-226° (ethanol).

후처리

  1. temperatureThe mixture was refluxed for 3 hours
  2. filtrationfiltered

출처 및 근거

ORD 기록
ord-2a4c795e95fc4a3f92251e0521578936
출처 데이터셋
uspto-grants-1976_06
특허 번호
US03963706

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