2-Butene, 1,4-dibromo- → HCID 54196002, 화합물

HRID 1658435노트

반응식

HRID 1658435 반응식
[Br:1][CH2:2][CH:3]=[CH:4][CH2:5]Br.[C:7]([O-:10])(=[O:9])[CH3:8].[Na+]>CN(C)C=O>[C:7]([O:10][CH2:5][CH:4]=[CH:3][CH2:2][Br:1])(=[O:9])[CH3:8]

참가 물질

4

반응물 2

HCID 131802-Butene, 1,4-dibromo-HCID 517045Sodium Acetate

생성물 1

HCID 54196002HCID 54196002, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

반응 조건

온도
100 °C

실험 절차

93 g of 1,4-dibromobut-2-ene are treated in 250 ml of dimethylformamide with 35.5 g of anhydrous sodium acetate and stirred for 1 hour at 100°C. The mixture is extensively freed from dimethylformamide on a rotary evaporator and the residue is partitioned between water and methylene chloride. The methylene chloride phase is dried over calcium chloride, filtered and concentrated. The residue is distilled under a water-jet vacuum, whereby the fractions are collected between 95° and 105°C at 10-15 mm; nD25 =1.502. There is obtained 1-acetoxy-4-bromobut-2-ene as a colourless liquid.

후처리

  1. customThe mixture is extensively freed from dimethylformamide on a rotary evaporator
  2. customthe residue is partitioned between water and methylene chloride
  3. dry with materialThe methylene chloride phase is dried over calcium chloride
  4. filtrationfiltered
  5. concentrationconcentrated
  6. distillationThe residue is distilled under a water-jet vacuum, whereby the fractions
  7. customare collected between 95° and 105°C at 10-15 mm

출처 및 근거

ORD 기록
ord-8ff3adfdd76a44619c366bf142486e45
출처 데이터셋
uspto-grants-1976_06
특허 번호
US03963777

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