Ethanol → N-(3-isopropoxypropyl)-N'-(2-octyl)-p-phenylenediamine

HRID 1658449노트

반응식

HRID 1658449 반응식
[CH:1]([O:4][CH2:5][CH2:6][CH2:7][NH:8][C:9]1[CH:14]=[CH:13][C:12]([NH2:15])=[CH:11][CH:10]=1)([CH3:3])[CH3:2].[CH3:16][CH:17](Br)[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].C(=O)([O-])[O-].[Na+].[Na+].C(O)C>O>[CH:1]([O:4][CH2:5][CH2:6][CH2:7][NH:8][C:9]1[CH:14]=[CH:13][C:12]([NH:15][CH:17]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH3:16])=[CH:11][CH:10]=1)([CH3:3])[CH3:2]

참가 물질

6

반응물 4

HCID 702EthanolHCID 10340Sodium CarbonateHCID 79046Sec-octyl bromide, (+-)-HCID 21529410N-(3-isopropoxypropyl)-p-phenylenediamine

생성물 1

HCID 21529417N-(3-isopropoxypropyl)-N'-(2-octyl)-p-phenylenediamine

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 50 g. of N-(3-isopropoxypropyl)-p-phenylenediamine, 50 g. of 2-octyl bromide, 200 ml. of 2N sodium carbonate and 1 liter of ethanol is stirred for 18 hours at 60°C. The reaction mixture is treated with 1 liter of water and extracted with 1 liter of ether. The ether layer is separated, washed with 1200 ml. of water, dried over sodium sulfate and evaporated in vacuo. A mixture of the residue in ether is treated with hydrogen chloride gas to yield the title product in dihydrochloride salt form, m.p. 200°-202°C.

후처리

  1. additionA mixture of 50 g
  2. extractionextracted with 1 liter of ether
  3. customThe ether layer is separated
  4. washwashed with 1200 ml
  5. dry with materialof water, dried over sodium sulfate
  6. customevaporated in vacuo
  7. additionA mixture of the residue in ether
  8. additionis treated with hydrogen chloride gas

출처 및 근거

ORD 기록
ord-b7c96a907a3a4aa2af5df0a06d2a85f6
출처 데이터셋
uspto-grants-1976_06
특허 번호
US03963780

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