Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Chlorotryptophan → N-formyl-6-chlorotryptophan
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Chlorotryptophan | HCID 65259 | — |
| 반응물 | Acetic-formic anhydride | HCID 75269 | — |
| 생성물 | N-formyl-6-chlorotryptophan | HCID 22791070 | — |
반응 단계
15 g(628 mM) of dl-6-chlorotryptophan was treated with 15 ml of acetic-formic anhydride. An exothermic reaction ensued, accompanied by solidification of the reaction slurry. Excess solvents were distilled off under vacuum and the resultant solids, after first leaching with dilute acid, were recrystallized from ethyl acetate to yield 12.45 g, 74%, of product, m.p. 181°-3° dec.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03965129 |
| 출처 데이터셋 | uspto-grants-1976_06 |
| ORD ID | ord-e51c20d4859a439eb115ed48f9e56aa1 |
| 출처 메모 | uspto-grants-1976_06 |