Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Trifluoromethylisobutyranilide → Ethyl-N-(3-trifluoromethylphenyl)isobutyrimidate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Trifluoromethylisobutyranilide | HCID 137264 | — |
| 반응물 | Triethyloxonium tetrafluoroborate | HCID 2723982 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Ethyl-N-(3-trifluoromethylphenyl)isobutyrimidate | HCID 21528116 | — |
반응 단계
Add a solution of 5.0 g. (0.03 moles) of triethyloxonium fluoborate in 13 ml. of dichloromethane to a solution of 7.3 g. (0.03 moles) of 3'-trifluoromethylisobutyranilide in 60 ml. of dichloromethane and reflux for 20 hours. Remove 50 ml. of dichloromethane and add 150 ml. of dry ether to precipitate out the product of this example as its fluoborate salt, m.p.=95°-100°C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03965176 |
| 출처 데이터셋 | uspto-grants-1976_06 |
| ORD ID | ord-9ca430cf61254486bff17b0e0f712086 |
| 출처 메모 | uspto-grants-1976_06 |