Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isocyanic acid → 2,5-Dimethyl-3,6-di(propan-2-yl)pyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isocyanic acid | HCID 6347 | — |
| 반응물 | Methyl Isobutyl Ketone | HCID 7909 | — |
| 반응물 | Nitrosyl chloride | HCID 17601 | — |
| 반응물 | 4-Methyl-3-oximino-2-pentanone | HCID 6795112 | — |
| 촉매 | Zinc | HCID 23994 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2,5-Dimethyl-3,6-di(propan-2-yl)pyrazine | HCID 13320992 | — |
반응 단계
2,5-Dimethyl-3,6-diisopropyl-pyrazine was prepared by first forming 4-methyl-3-oximino-2-pentanone by reacting 4-methyl-2-pentanone with nitrosyl chloride according to the method of BOUVEAULT, Bull. [3] 31, 1163 (1904). The autocondensation of two moles of the imino-ketone in the presence of zinc and acetic acid [according to the method described in Chimia 11, 310 (1957)] yielded 2,5-Dimethyl-3,6-diisopropyl-pyrazine which had a b.p. of 91° C./8 mm. Hg.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04303689 |
| 출처 데이터셋 | uspto-grants-1981_12 |
| ORD ID | ord-34eacce6e0c44de081c402173a06757b |
| 출처 메모 | uspto-grants-1981_12 |