Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate → 3'-Chloro-4'-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-biphenyl-2-carboxylic acid ethyl ester

반응식

[Br:1][c:2]1[cH:3][c:4]([Cl:21])[c:5]([CH2:6][CH:7]2[C:8](=[O:18])[N:9]([CH:12]3[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]3)[CH2:10][CH2:11]2)[cH:19][cH:20]1.[CH2:22]([CH3:23])[O:24][C:25]([c:26]1[c:27]([B:32]2[O:33][C:34]([CH3:35])([CH3:36])[C:37]([CH3:38])([CH3:39])[O:40]2)[cH:28][cH:29][cH:30][cH:31]1)=[O:41]>>[c:2]1(-[c:27]2[c:26]([C:25]([O:24][CH2:22][CH3:23])=[O:41])[cH:31][cH:30][cH:29][cH:28]2)[cH:3][c:4]([Cl:21])[c:5]([CH2:6][CH:7]2[C:8](=[O:18])[N:9]([CH:12]3[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]3)[CH2:10][CH2:11]2)[cH:19][cH:20]1

참가 물질

반응물 2

HCID 2773962Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

HCID 116822063-(4-Bromo-2-chlorobenzyl)-1-cyclohexylpyrrolidin-2-one

생성물 1

HCID 592993403'-Chloro-4'-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-biphenyl-2-carboxylic acid ethyl ester

출처 및 근거

ORD 기록: ord-985abab728f54af9aea872cc568dbea1
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

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