Pyridine → 1-naphthyl N-(N'-benzenesulfonyl-N'-methylaminosulfinyl)-N-methylcarbamate

HRID 1660520노트

반응식

HRID 1660520 반응식
[CH3:1][NH:2][C:3](=[O:15])[O:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[CH:7][CH:6]=1.N1C=CC=CC=1.[S:22](Cl)(Cl)=[O:23].[CH3:26][NH:27][S:28]([C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)(=[O:30])=[O:29]>O1CCCC1>[C:31]1([S:28]([N:27]([CH3:26])[S:22]([N:2]([CH3:1])[C:3](=[O:15])[O:4][C:5]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[CH:8]=[CH:7][CH:6]=2)=[O:23])(=[O:30])=[O:29])[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1

참가 물질

6

반응물 4

HCID 1049Pyridine2회HCID 6129CarbarylHCID 24386Thionyl ChlorideHCID 78858N-Methylbenzenesulfonamide

생성물 1

HCID 129599981-naphthyl N-(N'-benzenesulfonyl-N'-methylaminosulfinyl)-N-methylcarbamate

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

To a solution of 1-naphthyl methylcarbamate (4.0 g, 0.02 mol) in 20 ml dry tetrahydrofuran was added pyridine (2.0 g, 0.025 mol) followed by thionyl chloride (2.5 g, 0.021 mol). The mixture was stirred at room temperature for 4 hours. Pyridine (2 g, 0.025 mol) was added and followed by 3.5 g (0.02 mol) N-methylbenzenesulfonamide and the mixture was stirred at room temperature overnight.

후처리

  1. stirringthe mixture was stirred at room temperature overnight

출처 및 근거

ORD 기록
ord-e64338fb37b14dd495bd51008c144bd1
출처 데이터셋
uspto-grants-1981_12
특허 번호
US04308274

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