Diisopropylcarbodiimide → Phenylthiourea

HRID 1660670

반응식

HRID 1660670 반응식
C([C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11]([NH2:13])=[S:12])=[CH:6][CH:5]=1)(O)=O.CC(C)N=C=NC(C)C>CN(C=O)C>[C:7]1([NH:10][C:11]([NH2:13])=[S:12])[CH:8]=[CH:9][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 2

HCID 12734DiisopropylcarbodiimideHCID 7362164-Thioureidobenzoic acid

생성물 1

HCID 676454Phenylthiourea

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

4-carboxyphenylthiourea (Lancaster, 13047) was dissolved to 0.2M in DMF. The resultant mixture was activated by adding a half equivalent of DIC for 15 min at room temperature. Aminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651) were coated with the activated solution thus obtained and incubated for three hours at room temperature. The glass surfaces thus treated were then washed five times using respectively 30 mL of DMF for 3 minutes each at room temperature. After washing three times for three minutes each using respectively 30 mL of DCM at room temperature, the glass surfaces were dried and stored at 4° C. until further use.

후처리

  1. customAminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651)
  2. customthus obtained
  3. additionThe glass surfaces thus treated
  4. washwere then washed five times
  5. customfor 3 minutes
  6. customat room temperature
  7. washAfter washing three times for three minutes each using respectively 30 mL of DCM at room temperature
  8. customthe glass surfaces were dried
  9. customstored at 4° C. until further use

출처 및 근거

ORD 기록
ord-41314afdd5c447e7aa8917fc1c6e8c11
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08029979B2

연결된 노트

불러오는 중…