Methyl isothiocyanate → HCID 178432727, 화합물
반응식
[CH3:1][C:2]1[S:3][C:4]([C:8]([NH:10][NH2:11])=O)=[C:5]([CH3:7])[N:6]=1.[CH3:12][N:13]=[C:14]=[S:15]>C(O)C>[CH3:1][C:2]1[S:3][C:4]([C:8]2[N:13]([CH3:12])[C:14]([SH:15])=[N:11][N:10]=2)=[C:5]([CH3:7])[N:6]=1참가 물질
4
실험 절차
To a 2,4-dimethylthiazole-5-carbohydrazide (Prep26, 23 g, 0.13 mol) in ethanol (100 ml), methyl isothiocyanate (49.1 g, 0.67 mol) was added. The mixture was refluxed overnight. Then the ethanol was partially removed under vacuum and the residue was filtered. The solid was dried under vacuum to afford 14 g of the title compound (y=46%).
후처리
- temperatureThe mixture was refluxed overnight
- customThen the ethanol was partially removed under vacuum
- filtrationthe residue was filtered
- customThe solid was dried under vacuum
출처 및 근거
- ORD 기록
- ord-6a53f4a191fd4b9688199acb32574d83
- 출처 데이터셋
- uspto-grants-2011_10
- 특허 번호
- US08030322B2
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