10-Undecen-1-ol → (11-Hydroxy-undecyl)-(2,4,4-trimethylpentyl)-phosphinic acid

HRID 1661850

반응식

HRID 1661850 반응식
[CH3:1][CH:2]([CH2:7][C:8]([CH3:11])([CH3:10])[CH3:9])[CH2:3][PH:4](=[O:6])[OH:5].[CH2:12]([OH:23])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH:21]=[CH2:22]>C(OOC(CC)(C)C)(CC)(C)C>[OH:23][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][P:4]([CH2:3][CH:2]([CH3:1])[CH2:7][C:8]([CH3:10])([CH3:9])[CH3:11])(=[O:5])[OH:6]

참가 물질

4

반응물 2

HCID 818510-Undecen-1-olHCID 178460681HCID 178460681, 화합물

생성물 1

HCID 57909106(11-Hydroxy-undecyl)-(2,4,4-trimethylpentyl)-phosphinic acid수율 100.4%

시약·촉매·용매 1

HCID 25320Di-tert-amyl peroxide촉매

반응 조건

온도
140 °C

실험 절차

5 g (0.028 moles) of 2,4,4-trimethylpentyl phosphinic acid, 4.78 g (0.28 moles) of 10-undecen-1-ol and 0.3 mL (0.0014 moles) of di-tert-amylperoxide is mixed in a 50 mL single neck flask. The mixture is purged with argon to remove oxygen and is heated under argon for 5 hours at 140° C. Tert-amyl alcohol is removed by distillation and 9.8 g (quantitative yield) of (11-hydroxy-undecyl)-(2,4,4-trimethylpentyl)-phosphinic acid is obtained as a viscous oil.

후처리

  1. customThe mixture is purged with argon
  2. customto remove oxygen
  3. customTert-amyl alcohol is removed by distillation

출처 및 근거

ORD 기록
ord-fe181a46ac0145f28fe982b18644a501
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08030435B2

연결된 노트

불러오는 중…