Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) → Methyl 4-hydroxy-3-(2-methylprop-1-en-1-yl)benzoate
반응식
[CH3:1][C:2]([CH3:21])=[CH:3][C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][C:13]=1[O:14]C1CCCCO1)[C:7]([O:9][CH3:10])=[O:8].CC1C=CC(S([O-])(=O)=O)=CC=1.C1C=C[NH+]=CC=1>CO>[OH:14][C:13]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][C:4]=1[CH:3]=[C:2]([CH3:21])[CH3:1]참가 물질
4
실험 절차
To a stirred mixture of 66.20A (0.460 g, 2 mmol) in MeOH (8 mL) was added PPTS (0.04 g, 0.2 mmol). The reaction mixture was then stirred for 24 hours and then concentrated in vacuo. The residue was purified on silica gel (0-20% EtOAc in hexanes) to yield 66.20B as a colorless oil (0.320 g, 98% yield).
후처리
- concentrationconcentrated in vacuo
- customThe residue was purified on silica gel (0-20% EtOAc in hexanes)
출처 및 근거
- ORD 기록
- ord-66505642181142728716234bf9ff229e
- 출처 데이터셋
- uspto-grants-2011_10
- 특허 번호
- US08030354B2
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