(3-(5,5-Dimethylcyclopent-1-enyl)-4-(5-fluoro-2-methoxypyridin-4-yl)phenyl)methanol → 4-Chloromethyl-2-cyclopent-1-enyl-2'-fluoro-5'-methoxy-biphenyl
반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][C:3]=1[C:10]1[CH:15]=[CH:14][C:13]([CH2:16]O)=[CH:12][C:11]=1[C:18]1(OC)[CH2:22][CH2:21][CH2:20][CH2:19]1.[Cl:25]CC1C=CC(C2C(F)=CN=C(OC)C=2)=C(C2C(C)(C)CCC=2)C=1.CC1(C)C(C2C=C(CO)C=CC=2C2C(F)=CN=C(OC)C=2)=CCC1>>[Cl:25][CH2:16][C:13]1[CH:14]=[CH:15][C:10]([C:3]2[CH:4]=[C:5]([O:8][CH3:9])[CH:6]=[CH:7][C:2]=2[F:1])=[C:11]([C:18]2[CH2:22][CH2:21][CH2:20][CH:19]=2)[CH:12]=1참가 물질
4
반응물 3
생성물 1
실험 절차
Compound 66.68G was synthesized from 66.68F using a method analogous to the method used to prepare compound 66.12D from 66.12C. MS ESI m/e: 317.1 (M+1)+.