3,5-Dichloro-3-(2-methoxyphenyl)indolin-2-one → HCID 67428005, 화합물

HRID 1662664노트

반응식

HRID 1662664 반응식
Cl[C:2]1([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[O:19][CH3:20])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([Cl:11])[CH:9]=2)[NH:4][C:3]1=[O:12].FC(F)(F)C(O)=O.[NH2:28][C:29]1([C:34]([N:36]([CH3:38])[CH3:37])=[O:35])[CH2:33][CH2:32][CH2:31][CH2:30]1>>[Cl:11][C:8]1[CH:9]=[C:10]2[C:5](=[CH:6][CH:7]=1)[NH:4][C:3](=[O:12])[C:2]2([NH:28][C:29]1([C:34]([N:36]([CH3:38])[CH3:37])=[O:35])[CH2:33][CH2:32][CH2:31][CH2:30]1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[O:19][CH3:20]

참가 물질

3

반응물 2

HCID 219059133,5-Dichloro-3-(2-methoxyphenyl)indolin-2-oneHCID 67429037HCID 67429037, 화합물

생성물 1

HCID 67428005HCID 67428005, 화합물

실험 절차

With 0.81 g of 3,5-dichloro-3-(2-methoxyphenyl)-1,3-dihydro-2H-indol-2-one and the compound obtained in Step 76-3 (2.89 mmol, crude form) as starting materials, 0.27 g of the title compound (pale yellow solid) was obtained by a similar method to Step 4-2.

출처 및 근거

ORD 기록
ord-2be043b57172479493085ab8eb0e0177
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08030499B2

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