Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Acetoxy-2-bromoethane → tert-butyl (2S,4R)-2-[(dimethylamino)carbonyl]-4-(2-ethoxy-2-oxo ethoxy)pyrrolidine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Acetoxy-2-bromoethane | HCID 13564 | — |
| 반응물 | tert-butyl (2S,4S)-2-(dimethylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate | HCID 67430109 | — |
| 생성물 | tert-butyl (2S,4R)-2-[(dimethylamino)carbonyl]-4-(2-ethoxy-2-oxo ethoxy)pyrrolidine-1-carboxylate | HCID 67430579 | 46.1% |
반응 단계
With 20.0 g of tert-butyl (2S,4S)-2-[(dimethylamino)carbonyl]-4-hydroxypyrrolidine-1-carboxylate and 25.9 g of bromoethyl acetate as starting material, 12.3 g of the title compound obtained by a similar procedure to Step 139-1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08030499B2 |
| 출처 데이터셋 | uspto-grants-2011_10 |
| ORD ID | ord-e963e5333e174b09b5dbd2df29e79db1 |
| 출처 메모 | uspto-grants-2011_10 |