O-[(5-chlorothiophen-2-yl)methyl]hydroxylamine → HCID 11406179, 화합물

HRID 1663151노트

반응식

HRID 1663151 반응식
FC1C(O[C:9](=[O:24])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[NH:16][CH2:17][C:18]2[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=2)=C(F)C(F)=C(F)C=1F.[Cl:29][C:30]1[S:34][C:33]([CH2:35][O:36][NH2:37])=[CH:32][CH:31]=1>>[Cl:29][C:30]1[S:34][C:33]([CH2:35][O:36][NH:37][C:9](=[O:24])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[NH:16][CH2:17][C:18]2[CH:19]=[CH:20][N:21]=[CH:22][CH:23]=2)=[CH:32][CH:31]=1

참가 물질

3

반응물 2

HCID 10986580O-[(5-chlorothiophen-2-yl)methyl]hydroxylamineHCID 58989934HCID 58989934, 화합물

생성물 1

HCID 11406179HCID 11406179, 화합물

실험 절차

Prepared by the same method as described for example 415. Starting materials: 2-[(Pyridin-4-ylmethyl)-amino]-benzoic acid pentafluorophenyl ester (preparation 7C) and O-(5-chloro-thiophen-2-ylmethyl)-hydroxylamine (see preparation 64).

후처리

  1. customPrepared by the same method

출처 및 근거

ORD 기록
ord-271c68b0bd4446229fa4011e0fceeea4
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08034811B2

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