HCID 67217405, 화합물 → HCID 23627522, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([N:12]2[CH:25]([CH2:26][C:27]([OH:29])=O)[C:24]3[C:19](=[C:20]([F:31])[CH:21]=[C:22]([F:30])[CH:23]=3)[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]2=3)(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].Cl.Cl.[NH:34]1[CH2:38][CH2:37][N:36]=[C:35]1[C:39]1[CH:44]=[CH:43][C:42]([CH2:45][CH2:46][NH2:47])=[CH:41][CH:40]=1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([N:12]2[CH:25]([CH2:26][C:27]([NH:47][CH2:46][CH2:45][C:42]3[CH:43]=[CH:44][C:39]([C:35]4[NH:36][CH2:37][CH2:38][N:34]=4)=[CH:40][CH:41]=3)=[O:29])[C:24]3[C:19](=[C:20]([F:31])[CH:21]=[C:22]([F:30])[CH:23]=3)[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]2=3)(=[O:10])=[O:11])[CH:5]=[CH:6][C:7]=1[Cl:8]

참가 물질

반응물 2

HCID 67217405HCID 67217405, 화합물

HCID 67437251HCID 67437251, 화합물

생성물 1

HCID 23627522HCID 23627522, 화합물

실험 절차

The title compound was prepared from [5-(3,4-dichloro-benzenesulfonyl)-8,10-difluoro-5,6-dihydro-phenanthridin-6-yl]-acetic acid and 2-[4-(4,5-dihydro-1H-imidazol-2-yl)-phenyl]-ethylamine dihydrochloride (Reference Example 2) according to the method described in Example 1e. MS (EI) 656.1 (MH+).

출처 및 근거

ORD 기록: ord-071f269f09ad4693b28322c2f9d9c33f
출처 데이터셋: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08034827B2

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