Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triphenylphosphine → 3-Bromo-4-(3-methoxy-benzyloxy)-5-nitro-benzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triphenylphosphine | HCID 11776 | — |
| 반응물 | 3-Methoxybenzyl alcohol | HCID 81437 | — |
| 반응물 | ethyl N-ethoxycarbonyliminocarbamate | HCID 220568 | — |
| 반응물 | 3-Bromo-4-hydroxy-5-nitrobenzaldehyde | HCID 1494378 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-Bromo-4-(3-methoxy-benzyloxy)-5-nitro-benzaldehyde | HCID 86625158 | — |
반응 단계
To a solution of 3-bromo-4-hydroxy-5-nitro-benzaldehyde (87.4 mg) in dry dichloromethane (7.5 ml) was added 3-methoxybenzyl alcohol (35 μl), triphenylphosphine (103 mg) and diethyl azodicarboxylate (45 μl). The mixture was stirred under a nitrogen atmosphere for 17 h and then concentrated in vacuo. The residue was purified by chromatography on silicagel in heptane/ethyl acetate 9/1→1/1 (v/v) as eluent.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08034945B2 |
| 출처 데이터셋 | uspto-grants-2011_10 |
| ORD ID | ord-8058568de9b44bb98faec1b0d7f1cddd |
| 출처 메모 | uspto-grants-2011_10 |