Adipic Dihydrazide → Ceftiofur

참여 물질

반응 단계

Ceftiofur-HCl (50 mg) and adipic acid dihydrazide (10 mg) were placed in a 1-ml syringe. This syringe was connected to a second syringe containing 1 ml of oxidized dextran (Mw, 500,000; 85 mg/ml; 1 ml). The contents of the two syringes were mixed by making 20 reciprocations. A sample (200 μl) of the reaction mixture was transferred to a 2 ml centrifuge tube for the release experiment in PBS buffer. The release profile matrix appears in Table 4 below:

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